7C7A
Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ribonuclease MRP RNA subunit NME1 | polymer | 340 | 108806.7 | 1 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||
| 2 | B (B) | Ribonucleases P/MRP protein subunit POP1 | polymer | 875 | 100559.6 | 1 | UniProt (P41812) Pfam (PF06978) Pfam (PF08170) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP1,RNases P/MRP 100.4 kDa subunit |
| 3 | C (C) | Ribonucleases P/MRP protein subunit POP3 | polymer | 195 | 22643.7 | 1 | UniProt (P53833) Pfam (PF08228) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP3,RNases MRP/P 22.6 kDa subunit |
| 4 | D (D) | RNases MRP/P 32.9 kDa subunit | polymer | 279 | 32933.2 | 1 | UniProt (P38336) Pfam (PF01868) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP4 |
| 5 | E (E) | Ribonuclease P/MRP protein subunit POP5 | polymer | 173 | 19601.6 | 1 | UniProt (P28005) Pfam (PF01900) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP5,RNase P/MRP 19.6 kDa subunit |
| 6 | F (F) | Ribonucleases P/MRP protein subunit POP6 | polymer | 158 | 18235.0 | 1 | UniProt (P53218) Pfam (PF01918) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP6,RNases P/MRP 18.2 kDa subunit |
| 7 | G (G) | Ribonucleases P/MRP protein subunit POP7 | polymer | 140 | 15844.3 | 1 | UniProt (P38291) Pfam (PF12328) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP7,RNases P/MRP 15.8 kDa subunit |
| 8 | H (H) | Ribonucleases P/MRP protein subunit POP8 | polymer | 133 | 15530.4 | 1 | UniProt (P38208) Pfam (PF20976) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein POP8,RNases P/MRP 15.5 kDa subunit |
| 9 | I, J (I, J) | Ribonuclease P/MRP protein subunit RPP1 | polymer | 293 | 32270.3 | 2 | UniProt (P38786) Pfam (PF01876) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein RPP1,RNaseP/MRP 32.2 kDa subunit |
| 10 | K (K) | Ribonuclease MRP protein subunit SNM1 | polymer | 198 | 22579.0 | 1 | UniProt (P40993) Pfam (PF04032) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein SNM1,RNase MRP 22.5 kDa subunit |
| 11 | L (L) | Ribonuclease MRP protein subunit RMP1 | polymer | 201 | 23657.7 | 1 | UniProt (Q12530) Pfam (PF20945) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RNA-processing protein RMP1,RNase MRP 23.6 kDa subunit |
| 12 | M (R) | Internal Transcribed Spacer 1 | polymer | 21 | 6633.0 | 1 | Saccharomyces cerevisiae | ||
| 13 | N, O, Q (A, R) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 14 | P (K) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 451564.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 138.3 | |
| All* | Total formula weight | 451702.8 |
