7C6A
Crystal structure of AT2R-BRIL and SRP2070_Fab complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L | IgG Light Chain | polymer | 214 | 23681.1 | 1 | Mus musculus | ||
2 | H | IgG heavy chain | polymer | 224 | 24240.2 | 1 | Mus musculus | ||
3 | A | Type-2 angiotensin II receptor,Soluble cytochrome b562,Type-2 angiotensin II receptor | polymer | 422 | 48086.4 | 1 | UniProt (P50052) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361) In PDB | Homo sapiens (Human) | Angiotensin II type-2 receptor,AT2,Cytochrome b-562,Angiotensin II type-2 receptor,AT2 |
4 | B | SAR1, ILE8-ANGIOTENSIN II | polymer | 8 | 970.2 | 1 | UniProt (by SIFTS) (P01019) In PDB | Homo sapiens |
Sequence modifications
A: 35 - 242 (UniProt: P50052)
A: 1001 - 1106 (UniProt: P0ABE7)
A: 246 - 346 (UniProt: P50052)
PDB | External Database | Details |
---|---|---|
Gly 34 | - | expression tag |
Val 93 | Leu 93 | engineered mutation |
Trp 133 | Phe 133 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Trp 1007 | Met 29 | engineered mutation |
Ile 1102 | His 124 | engineered mutation |
Leu 1106 | Arg 128 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Glu 347 | - | expression tag |
Asn 348 | - | expression tag |
Leu 349 | - | expression tag |
Tyr 350 | - | expression tag |
Phe 351 | - | expression tag |
Gln 352 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 96977.8 | |
All* | Total formula weight | 96977.8 |