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7C5D

Crystal structure of TRF2 TRFH domain in complex with a MCPH1 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Telomeric repeat-binding factor 2polymer20423724.62UniProt (Q15554)
Pfam (PF08558)
Homo sapiens (Human)TRF2
2C, D
(C, D)
Microcephalinpolymer212429.62UniProt (Q8NEM0)Homo sapiens (Human)
3E, F
(B)
GLYCEROLnon-polymer92.12Chemie (GOL)
4G, H, I, J
(A, B, C, D)
waterwater18.0140Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight52308.6
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight52492.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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