7C40

MgGDP bound KRAS G12V

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	GTPase KRas	polymer	174	20013.5	1	UniProt (P01116) Pfam (PF00071) In PDB	Homo sapiens (Human)	K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
4		water	water		18.0	14	Chemie (HOH)

Sequence modifications

A: 1 - 168 (UniProt: P01116)

PDB	External Database	Details
Val 12	Gly 12	engineered mutation
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20013.5
Non-Polymers*	Number of molecules	2
	Total formula weight	467.5
All*	Total formula weight	20481.0

*Water molecules are not included.