7BUQ

mcGAS bound with 23-cGAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cyclic GMP-AMP synthase	polymer	507	58299.9	2	UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266)	Mus musculus (Mouse)	m-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (A, B)	cGAMP	non-polymer		674.4	2	Chemie (1SY)
4	G (A)	water	water		18.0	1	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	116599.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1479.6
All*	Total formula weight	118079.4

*Water molecules are not included.