7BTA
Crystal structure of Rheb D60K mutant bound to GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GTP-binding protein Rheb | polymer | 177 | 20163.1 | 2 | UniProt (Q15382) Pfam (PF00071) | Homo sapiens (Human) | Ras homolog enriched in brain |
| 2 | C, E (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 3 | D, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 169 (UniProt: Q15382)
| PDB | External Database | Details |
|---|---|---|
| Lys 60 | Asp 60 | engineered mutation |
| Leu 170 | - | expression tag |
| Glu 171 | - | expression tag |
| His 172 | - | expression tag |
| His 173 | - | expression tag |
| His 174 | - | expression tag |
| His 175 | - | expression tag |
| His 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40326.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1076.3 | |
| All* | Total formula weight | 41402.5 |
