7BL7

Crystal structure of UMPK from M. tuberculosis in complex with UDP and UTP (P21212 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (B, A, F, E, D...)	Uridylate kinase	polymer	281	29625.9	12	UniProt (P9WHK5) Pfam (PF00696)	Mycobacterium tuberculosis H37Rv	UK,Uridine monophosphate kinase,UMPK
2	BA, M, P, R, T... (H, B, E, D, C...)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	8	Chemie (UDP)
3	AA, N, O, Q, S... (G, A, F, D, C...)	URIDINE 5'-TRIPHOSPHATE	non-polymer		484.1	8	Chemie (UTP)
4	CA, DA, EA, FA, GA... (B, A, F, E, D...)	water	water		18.0	41	Chemie (HOH)

Sequence modifications

B, A, F, E, D, C, I, J, K, L, G, H: 1 - 261 (UniProt: P9WHK5)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	355510.7
Non-Polymers*	Number of molecules	16
	Total formula weight	7106.4
All*	Total formula weight	362617.1

*Water molecules are not included.