7BJY
Crystal structure of the first bromodomain (BD1) of human BRDT bound to Ro3280
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Isoform 2 of Bromodomain testis-specific protein | polymer | 113 | 13319.4 | 2 | UniProt (Q58F21) Pfam (PF00439) In PDB | Homo sapiens (Human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | A, B | 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide | non-polymer | 543.6 | 2 | Chemie (79C) | |||
| 3 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26638.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1211.4 | |
| All* | Total formula weight | 27850.1 |
