7B7G
BAZ2A bromodomain in complex with compounds MS04 and B11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 105 | 12363.9 | 1 | UniProt (Q9UIF9) Pfam (PF00439) | Homo sapiens (Human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
| 2 | B (A) | 5-ethyl-2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazole | non-polymer | 227.3 | 1 | Chemie (T1B) | |||
| 3 | C (A) | 1-[1-(3,5-dimethoxyphenyl)piperidin-4-yl]-2,3-dimethyl-guanidine | non-polymer | 306.4 | 1 | Chemie (T1E) | |||
| 4 | D (A) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1898 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
| His 1845 | Glu 1845 | engineered mutation |
| Ser 1848 | Leu 1848 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12363.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 533.7 | |
| All* | Total formula weight | 12897.5 |
