7B61
Crystal structure of MurE from E.coli in complex with Z57299526
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase | polymer | 496 | 53493.5 | 2 | UniProt (P22188) Pfam (PF01225) Pfam (PF08245) Pfam (PF02875) | Escherichia coli (strain K12) | Meso-A2pm-adding enzyme,Meso-diaminopimelate-adding enzyme,UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase,UDP-MurNAc-tripeptide synthetase,UDP-N-acetylmuramyl-tripeptide synthetase |
| 2 | C, I (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 3 | D, K (A, B) | (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide | non-polymer | 204.3 | 2 | Chemie (SYQ) | |||
| 4 | E, H (A, B) | (R)-N-(1-cyclopropylethyl)-6-methylpicolinamide | non-polymer | 204.3 | 2 | Chemie (T3Z) | |||
| 5 | F, G, L, M (A, B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 4 | Chemie (IPA) | |||
| 6 | J (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 7 | N, O (A, B) | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 495 (UniProt: P22188)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 106987.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1519.8 | |
| All* | Total formula weight | 108506.8 |
