7B5S
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Cullin-1 | polymer | 776 | 89800.4 | 1 | UniProt (Q13616) Pfam (PF00888) Pfam (PF10557) | Homo sapiens (Human) | CUL-1 |
| 2 | B (H) | E3 ubiquitin-protein ligase ARIH1 | polymer | 557 | 64197.8 | 1 | UniProt (Q9Y4X5) Pfam (PF21235) Pfam (PF00097) Pfam (PF01485) Pfam (PF22191) Pfam (PF19422) | Homo sapiens (Human) | H7-AP2,HHARI,Monocyte protein 6,MOP-6,Protein ariadne-1 homolog,ARI-1,UbcH7-binding protein,UbcM4-interacting protein,Ubiquitin-conjugating enzyme E2-binding protein 1 |
| 3 | C (R) | E3 ubiquitin-protein ligase RBX1 | polymer | 108 | 12290.0 | 1 | UniProt (P62877) Pfam (PF12678) | Homo sapiens (Human) | E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1 |
| 4 | D, E, F, G, H (H, R) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 166288.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 327.0 | |
| All* | Total formula weight | 166615.2 |
