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7B5S

Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1CCullin-1polymer77689800.41UniProt (Q13616)
Pfam (PF00888)
Pfam (PF10557)
In PDB
Homo sapiens (Human)CUL-1
2HE3 ubiquitin-protein ligase ARIH1polymer55764197.81UniProt (Q9Y4X5)
Pfam (PF21235)
Pfam (PF00097)
Pfam (PF01485)
Pfam (PF22191)
Pfam (PF19422)
In PDB
Homo sapiens (Human)H7-AP2,HHARI,Monocyte protein 6,MOP-6,Protein ariadne-1 homolog,ARI-1,UbcH7-binding protein,UbcM4-interacting protein,Ubiquitin-conjugating enzyme E2-binding protein 1
3RE3 ubiquitin-protein ligase RBX1polymer10812290.01UniProt (P62877)
Pfam (PF12678)
In PDB
Homo sapiens (Human)E3 ubiquitin-protein transferase RBX1,Protein ZYP,RING finger protein 75,RING-box protein 1,Rbx1,Regulator of cullins 1,ROC1
4H, RZINC IONnon-polymer65.45Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight166288.1
Non-Polymers*Number of molecules5
Total formula weight327.0
All*Total formula weight166615.2
*Water molecules are not included.

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PDB entries from 2024-07-24

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