7B44
Crystal structure of c-MET bound by compound S1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hepatocyte growth factor receptor | polymer | 299 | 33786.2 | 1 | UniProt (P08581) Pfam (PF07714) | Homo sapiens (Human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
| 2 | B (A) | 5-methoxy-1~{H}-indazole | non-polymer | 148.2 | 1 | Chemie (SVT) | |||
| 3 | C, D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | E, F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | I (A) | water | water | 18.0 | 266 | Chemie (HOH) |
Sequence modifications
A: 1049 - 1346 (UniProt: P08581)
| PDB | External Database | Details |
|---|---|---|
| Gly 1048 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33786.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 688.7 | |
| All* | Total formula weight | 34474.9 |
