7B3Z
Crystal structure of c-MET bound by compound 5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hepatocyte growth factor receptor | polymer | 299 | 33786.2 | 1 | UniProt (P08581) Pfam (PF07714) In PDB | Homo sapiens (Human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
3 | A | 3-[3-(phenylmethyl)-1~{H}-pyrrolo[2,3-b]pyridin-5-yl]-4,5-dihydro-1~{H}-pyrrolo[3,4-b]pyrrol-6-one | non-polymer | 328.4 | 1 | Chemie (SV8) | |||
4 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 1049 - 1346 (UniProt: P08581)
PDB | External Database | Details |
---|---|---|
Gly 1048 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33786.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 406.5 | |
All* | Total formula weight | 34192.7 |