7B3Z
Crystal structure of c-MET bound by compound 5
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | DIAMOND BEAMLINE I03 |
| Synchrotron site | Diamond |
| Beamline | I03 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2018-07-18 |
| Detector | DECTRIS PILATUS3 S 6M |
| Wavelength(s) | 0.97625 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 109.880, 42.450, 85.600 |
| Unit cell angles | 90.00, 120.86, 90.00 |
Refinement procedure
| Resolution | 21.340 - 1.800 |
| R-factor | 0.194 |
| Rwork | 0.193 |
| R-free | 0.21500 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | internal |
| RMSD bond length | 0.010 |
| RMSD bond angle | 0.940 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.6) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 21.340 | 1.830 |
| High resolution limit [Å] | 1.800 | 1.800 |
| Number of reflections | 31317 | 1480 |
| <I/σ(I)> | 10.9 | |
| Completeness [%] | 98.7 | |
| Redundancy | 3 | |
| CC(1/2) | 0.998 | 0.548 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 293 | 20 % PEG10000, 0.1 M Na-HEPES pH 7.5 |
