7B3Y

Structure of a nanoparticle for a COVID-19 vaccine candidate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Fibronectin binding protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	polymer	341	36000.7	1	UniProt (A0A0H3BX48) UniProt (Q9WXS1) Pfam (PF02986) Pfam (PF17802) Pfam (PF01081)	Streptococcus pyogenes serotype M49 (strain NZ131)

Sequence modifications

B: -127 - -15 (UniProt: A0A0H3BX48)

PDB	External Database	Details
Met -130	-	initiating methionine
Gly -129	-	expression tag
Ser -128	-	expression tag
Thr -125	Asp 868	conflict
Gly -118	Ser 875	conflict
Pro -114	Gln 879	conflict
Thr -108	Ile 885	conflict
Glu -93	Ile 900	conflict
Arg -90	Lys 903	conflict
His -65	Gln 928	conflict
Tyr -58	Met 935	conflict
Val -41	Ile 952	conflict
Pro -38	Ala 955	conflict
Glu -36	Thr 957	conflict
Asp -30	Gln 963	conflict
Asp -24	Asn 969	conflict
Glu -22	Lys 971	conflict
Glu -19	Lys 974	conflict
Thr -14	-	linker
Gly -13	-	linker
Gly -12	-	linker
Ser -11	-	linker
Gly -10	-	linker
Gly -9	-	linker
Ser -8	-	linker
Gly -7	-	linker
Gly -6	-	linker
Ser -5	-	linker
Gly -4	-	linker
Gly -3	-	linker
Ser -2	-	linker

B: -1 - 203 (UniProt: Q9WXS1)

PDB	External Database	Details
Lys 24	Glu 26	conflict
Leu 31	Glu 33	conflict
Met 59	Lys 61	conflict
Ala 74	Cys 76	conflict
Ala 98	Cys 100	conflict
Val 185	Asp 187	conflict
Ala 188	Arg 190	conflict
Gly 204	-	expression tag
Ser 205	-	expression tag
Gly 206	-	expression tag
Glu 207	-	expression tag
Pro 208	-	expression tag
Glu 209	-	expression tag
Ala 210	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36000.7
All*	Total formula weight	36000.7

*Water molecules are not included.