7B2M
Cryo-EM structure of complement C4b in complex with nanobody E3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement C4 beta chain | polymer | 656 | 71761.7 | 1 | UniProt (P0C0L4) Pfam (PF21145) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) | Homo sapiens (Human) | |
| 2 | B (B) | Complement C4 alpha chain | polymer | 767 | 84270.1 | 1 | UniProt (P0C0L4) Pfam (PF01821) Pfam (PF00207) Pfam (PF07678) Pfam (PF22661) | Homo sapiens (Human) | |
| 3 | C (C) | Complement C4 gamma chain | polymer | 291 | 33115.6 | 1 | UniProt (P0C0L4) Pfam (PF07677) Pfam (PF01759) | Homo sapiens (Human) | |
| 4 | D (D) | Anti-C4b nanobody E3 | polymer | 135 | 14489.0 | 1 | Lama glama (Llama) | ||
| 5 | E, F, G, H (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
B: 680 - 1446 (UniProt: P0C0L4)
| PDB | External Database | Details |
|---|---|---|
| Ser 1201 | Thr 1201 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 203636.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 204521.2 |
