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7B0Y

Structure of a transcribing RNA polymerase II-U1 snRNP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase II subunit RPB1polymer1970217450.11UniProt (P11414)
Pfam (PF04997)
Pfam (PF05001)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Pfam (PF04992)
Pfam (PF04990)
Sus scrofa domesticusRNA polymerase II subunit B1,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase III largest subunit
2B
(B)
DNA-directed RNA polymerase subunit betapolymer1174134041.41UniProt (A0A0B8RVL1)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF04566)
Pfam (PF04567)
Pfam (PF00562)
Pfam (PF04560)
Sus scrofa domesticus
3C
(C)
DNA-directed RNA polymerase II subunit RPB3polymer27531439.11UniProt (I3LCH3)
Pfam (PF01193)
Pfam (PF01000)
Sus scrofa domesticus
4D
(D)
DNA-directed RNA polymerase II subunit Dpolymer14216331.31UniProt (A0A287ADR4)
Pfam (PF03874)
Sus scrofa domesticus
5E
(E)
DNA-directed RNA polymerase II subunit Epolymer21024644.31UniProt (I3LSI7)
Pfam (PF03871)
Pfam (PF01191)
Sus scrofa domesticusRPB5 homolog
6F
(F)
DNA-directed RNA polymerase II subunit Fpolymer12714477.01UniProt (F1SKN8)
Pfam (PF01192)
UniProt (by SIFTS) (A0A4X1VEK9)
Sus scrofa domesticusDNA-directed RNA polymerases I,II,and III subunit RPABC2,RPB6 homolog
7G
(G)
DNA-directed RNA polymerase II subunit RPB7polymer17219314.31UniProt (I3LJZ9)Sus scrofa domesticus
8H
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer15017162.31UniProt (I3LCB2)
Pfam (PF03870)
Sus scrofa domesticus
9I
(I)
DNA-directed RNA polymerase II subunit RPB9polymer12514541.21UniProt (P60899)
Pfam (PF02150)
Pfam (PF01096)
Sus scrofa domesticusRNA polymerase II subunit B9,DNA-directed RNA polymerase II subunit I,RNA polymerase II 14.5 kDa subunit,RPB14.5
10J
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer677655.11UniProt (A0A4X1VYD0)
Pfam (PF01194)
Sus scrofa domesticus
11K
(K)
DNA-directed RNA polymerase II subunit RPB11-apolymer11713310.31UniProt (F1RKE4)
Pfam (PF13656)
Sus scrofa domesticus
12L
(L)
RPB12polymer587018.21UniProt (I3LN51)
Pfam (PF03604)
UniProt (by SIFTS) (A0A4X1TRS6)
Sus scrofa domesticus
13M
(N)
Non-template DNApolymer4814932.51synthetic construct
14N
(P)
145-nt RNApolymer14546784.91synthetic construct
15O
(T)
Template DNApolymer4814672.31synthetic construct
16P
(a)
U1 snRNApolymer16452697.11Homo sapiens (Human)
17Q
(b)
U1 small nuclear ribonucleoprotein 70 kDapolymer43751683.21UniProt (P08621)
Pfam (PF12220)
Pfam (PF00076)
Homo sapiens (Human)snRNP70
18R
(c)
U1 small nuclear ribonucleoprotein Apolymer28231319.51UniProt (P09012)
Pfam (PF00076)
Homo sapiens (Human)U1A
19S
(e)
Small nuclear ribonucleoprotein Sm D2polymer11813551.91UniProt (P62316)
Pfam (PF01423)
Homo sapiens (Human)Sm-D2,snRNP core protein D2
20T
(f)
Small nuclear ribonucleoprotein Fpolymer869734.21UniProt (P62306)
Pfam (PF01423)
Homo sapiens (Human)snRNP-F,Sm protein F,SmF
21U
(g)
Small nuclear ribonucleoprotein Epolymer9210817.61UniProt (P62304)
Pfam (PF01423)
Homo sapiens (Human)snRNP-E,Sm protein E,SmE
22V
(h)
Small nuclear ribonucleoprotein Gpolymer768508.11UniProt (P62308)
Pfam (PF01423)
Homo sapiens (Human)snRNP-G,Sm protein G,SmG
23W
(i)
Small nuclear ribonucleoprotein Sm D3polymer12613940.31UniProt (P62318)
Pfam (PF01423)
Homo sapiens (Human)Sm-D3,snRNP core protein D3
24X
(j)
Small nuclear ribonucleoprotein-associated proteinpolymer23123686.01UniProt (Q66K91)
Pfam (PF01423)
Homo sapiens (Human)
25Y
(k)
Small nuclear ribonucleoprotein Sm D1polymer11913310.71UniProt (P62314)
Pfam (PF01423)
Homo sapiens (Human)Sm-D1,Sm-D autoantigen,snRNP core protein D1
26AA, CA, DA, EA, FA...
(A, B, C, I, J...)
ZINC IONnon-polymer65.48Chemie (ZN)
27BA
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains25
Total formula weight823022.9
Non-Polymers*Number of molecules9
Total formula weight547.6
All*Total formula weight823570.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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