7B0Y

Structure of a transcribing RNA polymerase II-U1 snRNP complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0000974	cellular_component	Prp19 complex
A	0001055	molecular_function	RNA polymerase II activity
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0005634	cellular_component	nucleus
A	0005665	cellular_component	RNA polymerase II, core complex
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006366	biological_process	transcription by RNA polymerase II
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0031981	cellular_component	nuclear lumen
A	0032991	cellular_component	protein-containing complex
A	0033120	biological_process	positive regulation of RNA splicing
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0046872	molecular_function	metal ion binding
A	1990841	molecular_function	promoter-specific chromatin binding
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003676	molecular_function	nucleic acid binding
b	0003723	molecular_function	RNA binding
b	0003729	molecular_function	mRNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0006397	biological_process	mRNA processing
b	0016607	cellular_component	nuclear speck
b	0030619	molecular_function	U1 snRNA binding
b	0043462	biological_process	regulation of ATP-dependent activity
b	0043484	biological_process	regulation of RNA splicing
b	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
b	0061084	biological_process	negative regulation of protein refolding
b	0071004	cellular_component	U2-type prespliceosome
b	1904715	biological_process	negative regulation of chaperone-mediated autophagy
b	1990904	cellular_component	ribonucleoprotein complex
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0001055	molecular_function	RNA polymerase II activity
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0005654	cellular_component	nucleoplasm
B	0005665	cellular_component	RNA polymerase II, core complex
B	0006351	biological_process	DNA-templated transcription
B	0006366	biological_process	transcription by RNA polymerase II
B	0016779	molecular_function	nucleotidyltransferase activity
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046872	molecular_function	metal ion binding
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003676	molecular_function	nucleic acid binding
c	0003677	molecular_function	DNA binding
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0030619	molecular_function	U1 snRNA binding
c	0042802	molecular_function	identical protein binding
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	1990446	molecular_function	U1 snRNP binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005665	cellular_component	RNA polymerase II, core complex
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0046983	molecular_function	protein dimerization activity
D	0000166	molecular_function	nucleotide binding
D	0006352	biological_process	DNA-templated transcription initiation
D	0030880	cellular_component	RNA polymerase complex
D	0044237	biological_process	cellular metabolic process
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005737	cellular_component	cytoplasm
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0070062	cellular_component	extracellular exosome
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
E	0001054	molecular_function	RNA polymerase I activity
E	0001055	molecular_function	RNA polymerase II activity
E	0001056	molecular_function	RNA polymerase III activity
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0006351	biological_process	DNA-templated transcription
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0042797	biological_process	tRNA transcription by RNA polymerase III
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034715	cellular_component	pICln-Sm protein complex
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	0120114	cellular_component	Sm-like protein family complex
f	1903241	biological_process	U2-type prespliceosome assembly
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001650	cellular_component	fibrillar center
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0006351	biological_process	DNA-templated transcription
F	0006366	biological_process	transcription by RNA polymerase II
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005697	cellular_component	telomerase holoenzyme complex
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034715	cellular_component	pICln-Sm protein complex
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043229	cellular_component	intracellular organelle
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	1903241	biological_process	U2-type prespliceosome assembly
G	0003676	molecular_function	nucleic acid binding
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
h	0000245	biological_process	spliceosomal complex assembly
h	0000387	biological_process	spliceosomal snRNP assembly
h	0000398	biological_process	mRNA splicing, via spliceosome
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0005681	cellular_component	spliceosomal complex
h	0005682	cellular_component	U5 snRNP
h	0005683	cellular_component	U7 snRNP
h	0005684	cellular_component	U2-type spliceosomal complex
h	0005685	cellular_component	U1 snRNP
h	0005686	cellular_component	U2 snRNP
h	0005687	cellular_component	U4 snRNP
h	0005689	cellular_component	U12-type spliceosomal complex
h	0005737	cellular_component	cytoplasm
h	0005829	cellular_component	cytosol
h	0006397	biological_process	mRNA processing
h	0008380	biological_process	RNA splicing
h	0030532	cellular_component	small nuclear ribonucleoprotein complex
h	0034709	cellular_component	methylosome
h	0034719	cellular_component	SMN-Sm protein complex
h	0036261	biological_process	7-methylguanosine cap hypermethylation
h	0043186	cellular_component	P granule
h	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
h	0071004	cellular_component	U2-type prespliceosome
h	0071005	cellular_component	U2-type precatalytic spliceosome
h	0071007	cellular_component	U2-type catalytic step 2 spliceosome
h	0071011	cellular_component	precatalytic spliceosome
h	0071013	cellular_component	catalytic step 2 spliceosome
h	0097526	cellular_component	spliceosomal tri-snRNP complex
h	1903241	biological_process	U2-type prespliceosome assembly
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
H	0005634	cellular_component	nucleus
H	0005665	cellular_component	RNA polymerase II, core complex
H	0006351	biological_process	DNA-templated transcription
i	0000243	cellular_component	commitment complex
i	0000387	biological_process	spliceosomal snRNP assembly
i	0000398	biological_process	mRNA splicing, via spliceosome
i	0003723	molecular_function	RNA binding
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0005681	cellular_component	spliceosomal complex
i	0005682	cellular_component	U5 snRNP
i	0005683	cellular_component	U7 snRNP
i	0005684	cellular_component	U2-type spliceosomal complex
i	0005685	cellular_component	U1 snRNP
i	0005686	cellular_component	U2 snRNP
i	0005687	cellular_component	U4 snRNP
i	0005689	cellular_component	U12-type spliceosomal complex
i	0005697	cellular_component	telomerase holoenzyme complex
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0006396	biological_process	RNA processing
i	0006397	biological_process	mRNA processing
i	0006479	biological_process	protein methylation
i	0008380	biological_process	RNA splicing
i	0016604	cellular_component	nuclear body
i	0019899	molecular_function	enzyme binding
i	0030532	cellular_component	small nuclear ribonucleoprotein complex
i	0034709	cellular_component	methylosome
i	0034715	cellular_component	pICln-Sm protein complex
i	0034719	cellular_component	SMN-Sm protein complex
i	0036261	biological_process	7-methylguanosine cap hypermethylation
i	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
i	0070034	molecular_function	telomerase RNA binding
i	0071005	cellular_component	U2-type precatalytic spliceosome
i	0071007	cellular_component	U2-type catalytic step 2 spliceosome
i	0071011	cellular_component	precatalytic spliceosome
i	0071013	cellular_component	catalytic step 2 spliceosome
i	0071208	molecular_function	histone pre-mRNA DCP binding
i	0071209	molecular_function	U7 snRNA binding
i	0097526	cellular_component	spliceosomal tri-snRNP complex
i	1903241	biological_process	U2-type prespliceosome assembly
i	1990446	molecular_function	U1 snRNP binding
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006366	biological_process	transcription by RNA polymerase II
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0008270	molecular_function	zinc ion binding
I	0046872	molecular_function	metal ion binding
j	0000398	biological_process	mRNA splicing, via spliceosome
j	0003723	molecular_function	RNA binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0005682	cellular_component	U5 snRNP
j	0005685	cellular_component	U1 snRNP
j	0005686	cellular_component	U2 snRNP
j	0005687	cellular_component	U4 snRNP
j	0005737	cellular_component	cytoplasm
j	0043229	cellular_component	intracellular organelle
j	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
j	0071004	cellular_component	U2-type prespliceosome
j	0071013	cellular_component	catalytic step 2 spliceosome
j	0071204	cellular_component	histone pre-mRNA 3'end processing complex
j	0071208	molecular_function	histone pre-mRNA DCP binding
j	1990446	molecular_function	U1 snRNP binding
j	1990447	molecular_function	U2 snRNP binding
j	1990904	cellular_component	ribonucleoprotein complex
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0001054	molecular_function	RNA polymerase I activity
J	0001055	molecular_function	RNA polymerase II activity
J	0001056	molecular_function	RNA polymerase III activity
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005736	cellular_component	RNA polymerase I complex
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006366	biological_process	transcription by RNA polymerase II
J	0008270	molecular_function	zinc ion binding
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
k	0000243	cellular_component	commitment complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005684	cellular_component	U2-type spliceosomal complex
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005689	cellular_component	U12-type spliceosomal complex
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0006396	biological_process	RNA processing
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0030532	cellular_component	small nuclear ribonucleoprotein complex
k	0034709	cellular_component	methylosome
k	0034715	cellular_component	pICln-Sm protein complex
k	0034719	cellular_component	SMN-Sm protein complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043229	cellular_component	intracellular organelle
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0071005	cellular_component	U2-type precatalytic spliceosome
k	0071007	cellular_component	U2-type catalytic step 2 spliceosome
k	0071011	cellular_component	precatalytic spliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	0097526	cellular_component	spliceosomal tri-snRNP complex
k	1903241	biological_process	U2-type prespliceosome assembly
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0001055	molecular_function	RNA polymerase II activity
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
K	0006351	biological_process	DNA-templated transcription
K	0006366	biological_process	transcription by RNA polymerase II
K	0046983	molecular_function	protein dimerization activity
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
L	0005634	cellular_component	nucleus
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005736	cellular_component	RNA polymerase I complex
L	0006351	biological_process	DNA-templated transcription
L	0006366	biological_process	transcription by RNA polymerase II
L	0008270	molecular_function	zinc ion binding
L	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI

Chain	Residue	Details
C	ASP136-ILE148

---

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA

Chain	Residue	Details
A	TYR1593-ALA1599
A	TYR1671-SER1677
A	TYR1678-SER1684
A	TYR1685-SER1691
A	TYR1692-SER1698
A	TYR1699-SER1705
A	TYR1706-SER1712
A	TYR1713-SER1719
A	TYR1720-SER1726
A	TYR1727-SER1733
A	TYR1734-SER1740
A	TYR1615-SER1621
A	TYR1741-ASN1747
A	TYR1748-ASN1754
A	TYR1755-SER1761
A	TYR1762-SER1768
A	TYR1769-ASN1775
A	TYR1776-ASN1782
A	TYR1783-SER1789
A	TYR1790-SER1796
A	TYR1797-SER1803
A	TYR1818-SER1824
A	TYR1622-SER1628
A	TYR1825-SER1831
A	TYR1832-LYS1838
A	TYR1839-SER1845
A	TYR1853-LYS1859
A	TYR1860-LYS1866
A	TYR1867-LYS1873
A	TYR1874-THR1880
A	TYR1888-THR1894
A	TYR1902-LYS1908
A	TYR1909-THR1915
A	TYR1629-ASN1635
A	TYR1916-LYS1922
A	TYR1923-THR1929
A	TYR1930-LYS1936
A	TYR1947-THR1953
A	TYR1636-SER1642
A	TYR1643-SER1649
A	TYR1650-SER1656
A	TYR1657-SER1663
A	TYR1664-SER1670

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH

Chain	Residue	Details
I	TYR112-HIS118

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP

Chain	Residue	Details
C	ASN32-PRO72

---

site_id	PS00466
Number of Residues	38
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW

Chain	Residue	Details
I	CYS86-TRP123

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC

Chain	Residue	Details
I	PHE16-CYS42

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE

Chain	Residue	Details
E	HIS142-GLU155

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ

Chain	Residue	Details
F	THR58-GLN72

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP

Chain	Residue	Details
K	ILE35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
B	GLY932-THR944

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
k	LYS86
A	LYS346
A	ARG358
A	ARG460
A	ASP499
A	ARG1416
A	ARG1421

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
e	SER9
A	ASP495
A	CYS74
A	CYS81
A	HIS84
A	CYS111
A	CYS114
A	CYS154
A	CYS184
A	ASN493

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
e	THR12
I	CYS20
I	CYS39
I	CYS42

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
e	LYS6
I	CYS89
e	LYS8
I	CYS119

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
b	SER268
A	SER1868
A	SER1875
A	SER1878
A	SER1882
A	SER1896
A	SER1899
A	SER1906
A	SER1913
A	SER1917
A	SER1920
A	SER217
A	SER1927
A	SER1931
A	SER1934
A	SER1843
A	SER1845
A	SER1849
A	SER1850
A	SER1857
A	SER1861
A	SER1864

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
b	SER320

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
b	SER410

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
b	LYS346

---

site_id	SWS_FT_FI9
Number of Residues	12
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P24928

Chain	Residue	Details
A	THR1840
A	THR1926
A	THR1929
A	THR1933
A	THR1854
A	THR1863
A	THR1870
A	THR1877
A	THR1885
A	THR1912
A	THR1915
A	THR1919

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P08775

Chain	Residue	Details
A	SER1847

---

site_id	SWS_FT_FI11
Number of Residues	6
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P24928

Chain	Residue	Details
A	LYS1859
A	LYS1866
A	LYS1873
A	LYS1887
A	LYS1922
A	LYS1936

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P24928

Chain	Residue	Details
A	TYR1860
A	TYR1867
A	TYR1874
A	TYR1881
A	TYR1909
A	TYR1916
A	TYR1923
A	TYR1930

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P08775

Chain	Residue	Details
A	THR1894

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	MOD_RES: N6,N6-dimethyllysine => ECO:0000250|UniProtKB:P08775

Chain	Residue	Details
A	LYS1908

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); by NEDD4 => ECO:0000250|UniProtKB:P24928

Chain	Residue	Details
A	LYS1268

---