7AYC

Crystal Structure of human mitochondrial 2-Enoyl Thioester Reductase (MECR) with single mutation G165Q

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Enoyl-[acyl-carrier-protein] reductase, mitochondrial	polymer	352	38364.1	1	UniProt (Q9BV79) Pfam (PF08240) Pfam (PF00107) In PDB	Homo sapiens (Human)	2-enoyl thioester reductase,Nuclear receptor-binding factor 1,NRBF-1
2	A	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
3		water	water		18.0	59	Chemie (HOH)

Sequence modifications

A: 31 - 373 (UniProt: Q9BV79)

PDB	External Database	Details
Met 30	-	initiating methionine
Leu 96	Phe 96	variant
Gln 165	Gly 165	engineered mutation
Leu 374	-	expression tag
Glu 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38364.1
Non-Polymers*	Number of molecules	3
	Total formula weight	106.4
All*	Total formula weight	38470.4

*Water molecules are not included.