7AYA
Crystal structure of CK2 bound by compound 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Casein kinase II subunit alpha | polymer | 342 | 40982.7 | 2 | UniProt (P68400) Pfam (PF00069) | Homo sapiens (Human) | CK II alpha |
| 2 | C, D, E, F, G... (A, B) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | AA, BA, CA, DA, EA... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 26 | Chemie (EDO) | |||
| 4 | NA, U (B, A) | ~{N}-[2-[(1~{R},2~{R})-2-(aminomethyl)cyclopropyl]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]ethanamide | non-polymer | 416.5 | 2 | Chemie (S8W) | |||
| 5 | OA, PA (A, B) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 336 (UniProt: P68400)
| PDB | External Database | Details |
|---|---|---|
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 81965.4 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 3407.4 | |
| All* | Total formula weight | 85372.7 |
