7AXF
Crystal structure of the hPXR-LBD in complex with pretilachlor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Nuclear receptor subfamily 1 group I member 2 | polymer | 316 | 36280.9 | 1 | UniProt (O75469) Pfam (PF00104) | Homo sapiens (Human) | Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor,Steroid and xenobiotic receptor,SXR |
2 | B, C (A) | pretilachlor | non-polymer | 311.8 | 2 | Chemie (S6T) | |||
3 | D, E, F, G, H (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 5 | Chemie (IPA) | |||
4 | I (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 130 - 434 (UniProt: O75469)
PDB | External Database | Details |
---|---|---|
Met 119 | - | initiating methionine |
Lys 120 | - | expression tag |
Lys 121 | - | expression tag |
Gly 122 | - | expression tag |
His 123 | - | expression tag |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
Gly 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36280.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 924.2 | |
All* | Total formula weight | 37205.0 |