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7AX4

Human TYK2 pseudokinase domain (575-869) in complex with 5-(4-Fluoro-phenyl)-2-ureido-thiophene-3-carboxylic acid amide.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BNon-receptor tyrosine-protein kinase TYK2polymer29532988.42UniProt (P29597)
Pfam (PF07714)
In PDB
Homo sapiens (Human)
2A, B2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamidenon-polymer279.32Chemie (NM7)
3A, BCALCIUM IONnon-polymer40.12Chemie (CA)
4waterwater18.0408Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65976.9
Non-Polymers*Number of molecules4
Total formula weight638.7
All*Total formula weight66615.6
*Water molecules are not included.

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PDB entries from 2024-05-15

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