7AX4

Human TYK2 pseudokinase domain (575-869) in complex with 5-(4-Fluoro-phenyl)-2-ureido-thiophene-3-carboxylic acid amide.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Non-receptor tyrosine-protein kinase TYK2	polymer	295	32988.4	2	UniProt (P29597) Pfam (PF07714)	Homo sapiens (Human)
2	C, E (A, B)	2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide	non-polymer		279.3	2	Chemie (NM7)
3	D, F (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	G, H (A, B)	water	water		18.0	408	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65976.9
Non-Polymers*	Number of molecules	4
	Total formula weight	638.7
All*	Total formula weight	66615.6

*Water molecules are not included.