7AX1

Crystal structure of the human CCR4-CAF1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CCR4-NOT transcription complex subunit 6	polymer	563	64049.2	1	UniProt (Q9ULM6) Pfam (PF13855) Pfam (PF03372) In PDB	Homo sapiens (Human)	CCR4 carbon catabolite repression 4-like,Carbon catabolite repressor protein 4 homolog,Cytoplasmic deadenylase
2	B	CCR4-NOT transcription complex subunit 7	polymer	290	33310.6	1	UniProt (Q9UIV1) Pfam (PF04857) In PDB	Homo sapiens (Human)	BTG1-binding factor 1,CCR4-associated factor 1,CAF-1,Caf1a
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

A: 1 - 557 (UniProt: Q9ULM6)

PDB	External Database	Details
Gly -5	-	expression tag
Pro -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag

B: 2 - 285 (UniProt: Q9UIV1)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Leu 0	-	expression tag
Glu 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97359.8
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	97408.4

*Water molecules are not included.