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7AWL

Structure of the thermostabilized EAAT1 cryst-II mutant in complex with barium and the allosteric inhibitor UCPH101

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AExcitatory amino acid transporter 1, Neutral amino acid transporter, Excitatory amino acid transporter, Transporter proteinpolymer52256460.31Pfam (PF00375)
UniProt (by SIFTS) (P43003)
UniProt (by SIFTS) (Q15758)
In PDB
Homo sapiens (Human)
2A2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrilenon-polymer422.51Chemie (6Z6)
3ABARIUM IONnon-polymer137.32Chemie (BA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight56460.3
Non-Polymers*Number of molecules3
Total formula weight697.1
All*Total formula weight57157.5
*Water molecules are not included.

224004

PDB entries from 2024-08-21

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