7AUW
Inhibitory complex of human meprin beta with mouse fetuin-B.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Meprin A subunit beta | polymer | 550 | 62468.4 | 2 | UniProt (Q16820) Pfam (PF01400) Pfam (PF00629) Pfam (PF22486) | Homo sapiens (Human) | Endopeptidase-2,Meprin B,N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta,PABA peptide hydrolase,PPH beta |
| 2 | B, D (B, D) | Fetuin-B | polymer | 394 | 43590.5 | 2 | UniProt (Q9QXC1) Pfam (PF00031) | Mus musculus (Mouse) | Fetuin-like protein IRL685 |
| 3 | E, G, M, O (E, G, M, O) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1203.1 | 4 | In PDB GlyTouCan (G11460AB) | |||
| 4 | F, N, T (F, N, T) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | H, P (H, P) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1041.0 | 2 | In PDB GlyTouCan (G88303DD) | |||
| 6 | I, Q (I, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 7 | J, R (J, R) | alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 2045.8 | 2 | In PDB GlyTouCan (G19958IL) | |||
| 8 | K, S (K, S) | alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 513.5 | 2 | In PDB GlyTouCan (G04836KE) | |||
| 9 | L (L) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G18638YB) | |||
| 10 | U (U) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G11971MR) | |||
| 11 | V, Z (A, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 12 | AA, W (C, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 13 | BA, X (C, A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 14 | Y (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 15 | CA, DA, EA, FA (A, B, C, D) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A, C: 62 - 608 (UniProt: Q16820)
B, D: 1 - 388 (UniProt: Q9QXC1)
| PDB | External Database | Details |
|---|---|---|
| Pro 609 | - | expression tag |
| Ser 610 | - | expression tag |
| Lys 611 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
| His 393 | - | expression tag |
| His 394 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 212117.8 | |
| Branched | Number of molecules | 17 |
| Total formula weight | 16216.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 590.1 | |
| All* | Total formula weight | 228924.8 |
