7AUC
Crystal structure of an engineered helicase domain construct for human Bloom syndrome protein (BLM)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bloom syndrome protein,Bloom syndrome protein | polymer | 562 | 63884.5 | 1 | UniProt (P54132) Pfam (PF00270) Pfam (PF00271) Pfam (PF16124) Pfam (PF00570) In PDB | Homo sapiens (Human) | DNA helicase,RecQ-like type 2,RecQ2,RecQ protein-like 3,DNA helicase,RecQ-like type 2,RecQ2,RecQ protein-like 3 |
2 | A | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
8 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
9 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
10 | water | water | 18.0 | 431 | Chemie (HOH) |
Sequence modifications
A: 636 - 1196 (UniProt: P54132)
A: 1202 - 1298 (UniProt: P54132)
PDB | External Database | Details |
---|---|---|
Met 611 | - | initiating methionine |
Gly 612 | - | expression tag |
Ser 613 | - | expression tag |
Ala 614 | - | expression tag |
Trp 615 | - | expression tag |
Ser 616 | - | expression tag |
His 617 | - | expression tag |
Pro 618 | - | expression tag |
Gln 619 | - | expression tag |
Phe 620 | - | expression tag |
Glu 621 | - | expression tag |
Lys 622 | - | expression tag |
Ser 623 | - | expression tag |
Ser 624 | - | expression tag |
Gly 625 | - | expression tag |
Leu 626 | - | expression tag |
Glu 627 | - | expression tag |
Val 628 | - | expression tag |
Leu 629 | - | expression tag |
Phe 630 | - | expression tag |
Gln 631 | - | expression tag |
Gly 632 | - | expression tag |
Pro 633 | - | expression tag |
His 634 | - | expression tag |
Met 635 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 1197 | - | linker |
Ser 1198 | - | linker |
Gly 1199 | - | linker |
Gly 1200 | - | linker |
Ser 1201 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63884.5 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 1710.5 | |
All* | Total formula weight | 65595.0 |