7ARX
Crystal structure of the catalytic fragment of masp-1 in complex with SFMI1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mannan-binding lectin serine protease 1 | polymer | 155 | 17508.2 | 1 | UniProt (P48740) Pfam (PF00084) In PDB | Homo sapiens (human) | Complement factor MASP-3,Complement-activating component of Ra-reactive factor,Mannose-binding lectin-associated serine protease 1,MASP-1,Mannose-binding protein-associated serine protease,Ra-reactive factor serine protease p100,RaRF,Serine protease 5 |
| 2 | B | Mannan-binding lectin serine protease 1 | polymer | 251 | 28028.8 | 1 | UniProt (P48740) Pfam (PF00089) In PDB | Homo sapiens (human) | Complement factor MASP-3,Complement-activating component of Ra-reactive factor,Mannose-binding lectin-associated serine protease 1,MASP-1,Mannose-binding protein-associated serine protease,Ra-reactive factor serine protease p100,RaRF,Serine protease 5 |
| 3 | C | SFMI1 - Sunflower MASP1 inhibitor | polymer | 14 | 1471.8 | 1 | UniProt (by SIFTS) (Q4GWU5) In PDB | Helianthus annuus | |
| 4 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 298 - 448 (UniProt: P48740)
| PDB | External Database | Details |
|---|---|---|
| Ala 294 | - | expression tag |
| Ser 295 | - | expression tag |
| Met 296 | - | expression tag |
| Thr 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 47008.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 106.1 | |
| All* | Total formula weight | 47115.0 |
