7AR4
Crystal structure of beta-catenin in complex with cyclic peptide inhibitor
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AAA | Catenin beta-1 | polymer | 536 | 58412.7 | 1 | UniProt (P35222) Pfam (PF00514) In PDB | Homo sapiens (Human) | Beta-catenin |
2 | PaP | Cadherin-1 | polymer | 16 | 1714.9 | 1 | UniProt (P09803) In PDB | Mus musculus | ARC-1,Epithelial cadherin,E-cadherin,Uvomorulin |
3 | AAA | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | AAA | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
AAA: 134 - 665 (UniProt: P35222)
PaP: 1 - 16 (UniProt: P09803)
PDB | External Database | Details |
---|---|---|
Gly 130 | - | expression tag |
Ala 131 | - | expression tag |
Met 132 | - | expression tag |
Ala 133 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Bal 1 | Glu 783 | engineered mutation |
Dpr 8 | Ala 790 | engineered mutation |
Asp 10 | Thr 792 | engineered mutation |
Ser 11 | Leu 793 | engineered mutation |
Leu 12 | Met 794 | engineered mutation |
Leu 13 | Ser 795 | engineered mutation |
Phe 15 | Pro 797 | engineered mutation |
Bal 16 | Gln 798 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 60127.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 273.8 | |
All* | Total formula weight | 60401.4 |