7AQQ
Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 119 | 13941.4 | 1 | UniProt (P92533) Pfam (PF00507) | Arabidopsis thaliana (Mouse-ear cress) | NADH dehydrogenase subunit 3 |
| 2 | B (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 325 | 36020.1 | 1 | UniProt (B5TM92) Pfam (PF00146) UniProt (by SIFTS) (P92558) | Arabidopsis thaliana (Mouse-ear cress) | |
| 3 | C (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 205 | 23690.4 | 1 | UniProt (A0A2P2CLG1) Pfam (PF00499) UniProt (by SIFTS) (P60497) | Arabidopsis thaliana (Mouse-ear cress) | |
| 4 | D (K) | NADH dehydrogenase subunit 4L | polymer | 100 | 11165.5 | 1 | UniProt (A0A2P2CLH7) Pfam (PF00420) UniProt (by SIFTS) (Q04614) | Arabidopsis thaliana (Mouse-ear cress) | |
| 5 | E (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 669 | 74498.0 | 1 | UniProt (B5TM94) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) UniProt (by SIFTS) (P29388) | Arabidopsis thaliana (Mouse-ear cress) | |
| 6 | F (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 495 | 56055.8 | 1 | UniProt (B5TM93) Pfam (PF00361) UniProt (by SIFTS) (P93313) | Arabidopsis thaliana (Mouse-ear cress) | |
| 7 | G (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 499 | 55486.8 | 1 | UniProt (O05000) Pfam (PF00361) | Arabidopsis thaliana (Mouse-ear cress) | NADH dehydrogenase subunit 2 |
| 8 | H (O) | AT3G07480.1 | polymer | 159 | 17626.2 | 1 | UniProt (A0A384LA38) UniProt (by SIFTS) (Q9SRR8) | Arabidopsis thaliana (Mouse-ear cress) | |
| 9 | I (X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-B | polymer | 106 | 11986.0 | 1 | UniProt (Q8LGE7) Pfam (PF06747) | Arabidopsis thaliana (Mouse-ear cress) | |
| 10 | J (Z) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-A | polymer | 143 | 16145.6 | 1 | UniProt (Q8RWA7) Pfam (PF06212) | Arabidopsis thaliana (Mouse-ear cress) | Protein MATERNAL EFFECT EMBRYO ARREST 4 |
| 11 | K (a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 65 | 7349.6 | 1 | UniProt (Q9C9Z5) Pfam (PF15879) | Arabidopsis thaliana (Mouse-ear cress) | |
| 12 | L (b) | At2g46540/F11C10.23 | polymer | 65 | 6810.2 | 1 | UniProt (Q9ZPY5) | Arabidopsis thaliana (Mouse-ear cress) | Expressed protein,F11C10.23/F11C10.23,Fiber |
| 13 | M (d) | Excitatory amino acid transporter | polymer | 81 | 9220.7 | 1 | UniProt (Q94AL6) | Arabidopsis thaliana (Mouse-ear cress) | |
| 14 | N (e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-B | polymer | 83 | 9914.1 | 1 | UniProt (Q9LZI6) Pfam (PF10200) | Arabidopsis thaliana (Mouse-ear cress) | |
| 15 | O (f) | At4g16450 | polymer | 106 | 11355.0 | 1 | UniProt (Q84W12) Pfam (PF10785) | Arabidopsis thaliana (Mouse-ear cress) | NADH-ubiquinone oxidoreductase |
| 16 | P (i) | P1 | polymer | 98 | 11808.2 | 1 | UniProt (A0A178W1I8) Pfam (PF17250) UniProt (by SIFTS) (Q9FYF8) | Arabidopsis thaliana (Mouse-ear cress) | |
| 17 | Q (u) | unknown | polymer | 30 | 2571.2 | 1 | Arabidopsis thaliana (Mouse-ear cress) | ||
| 18 | R (v) | Uncharacterized protein At2g27730, mitochondrial | polymer | 113 | 11965.5 | 1 | UniProt (Q9ZUX4) | Arabidopsis thaliana (Mouse-ear cress) | |
| 19 | S (x) | Gamma carbonic anhydrase-like 2, mitochondrial | polymer | 256 | 27985.1 | 1 | UniProt (Q9SMN1) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CAL2 |
| 20 | T (y) | Gamma carbonic anhydrase 2, mitochondrial | polymer | 278 | 30102.2 | 1 | UniProt (Q9C6B3) Pfam (PF00132) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CA2,Transcription factor APFI |
| 21 | U (z) | Gamma carbonic anhydrase 1, mitochondrial | polymer | 275 | 30010.0 | 1 | UniProt (Q9FWR5) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CA1 |
| 22 | V (H) | Ubiquinone-9 | non-polymer | 795.2 | 1 | Chemie (UQ9) | |||
| 23 | W, Y (H, N) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 2 | Chemie (PTY) | |||
| 24 | X (M) | Lauryl Maltose Neopentyl Glycol | non-polymer | 1005.2 | 1 | Chemie (LMN) | |||
| 25 | Z (O) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 26 | AA (v) | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE | non-polymer | 763.1 | 1 | Chemie (PC7) | |||
| 27 | BA (y) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 28 | CA (y) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 1 | Chemie (PGT) | |||
| 29 | DA (z) | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE | non-polymer | 455.4 | 1 | Chemie (PSF) | |||
| 30 | EA (z) | Phosphatidylinositol | non-polymer | 887.1 | 1 | Chemie (T7X) |
Sequence modifications
L: 1 - 669 (UniProt: B5TM94)
M: 1 - 495 (UniProt: B5TM93)
| PDB | External Database | Details |
|---|---|---|
| Phe 91 | Ser 91 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 326 | Pro 326 | conflict |
| Phe 378 | Ser 378 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 21 |
| Total formula weight | 475707.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 6246.4 | |
| All* | Total formula weight | 481954.1 |
