7AQQ
Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NADH-ubiquinone oxidoreductase chain 3 | polymer | 119 | 13941.4 | 1 | UniProt (P92533) Pfam (PF00507) | Arabidopsis thaliana (Mouse-ear cress) | NADH dehydrogenase subunit 3 |
| 2 | B (H) | NADH-ubiquinone oxidoreductase chain 1 | polymer | 325 | 36020.1 | 1 | UniProt (B5TM92) Pfam (PF00146) UniProt (by SIFTS) (P92558) | Arabidopsis thaliana (Mouse-ear cress) | |
| 3 | C (J) | NADH-ubiquinone oxidoreductase chain 6 | polymer | 205 | 23690.4 | 1 | UniProt (A0A2P2CLG1) Pfam (PF00499) UniProt (by SIFTS) (P60497) | Arabidopsis thaliana (Mouse-ear cress) | |
| 4 | D (K) | NADH dehydrogenase subunit 4L | polymer | 100 | 11165.5 | 1 | UniProt (A0A2P2CLH7) Pfam (PF00420) UniProt (by SIFTS) (Q04614) | Arabidopsis thaliana (Mouse-ear cress) | |
| 5 | E (L) | NADH-ubiquinone oxidoreductase chain 5 | polymer | 669 | 74498.0 | 1 | UniProt (B5TM94) Pfam (PF00662) Pfam (PF00361) Pfam (PF06455) UniProt (by SIFTS) (P29388) | Arabidopsis thaliana (Mouse-ear cress) | |
| 6 | F (M) | NADH-ubiquinone oxidoreductase chain 4 | polymer | 495 | 56055.8 | 1 | UniProt (B5TM93) Pfam (PF00361) UniProt (by SIFTS) (P93313) | Arabidopsis thaliana (Mouse-ear cress) | |
| 7 | G (N) | NADH-ubiquinone oxidoreductase chain 2 | polymer | 499 | 55486.8 | 1 | UniProt (O05000) Pfam (PF00361) | Arabidopsis thaliana (Mouse-ear cress) | NADH dehydrogenase subunit 2 |
| 8 | H (O) | AT3G07480.1 | polymer | 159 | 17626.2 | 1 | UniProt (A0A384LA38) UniProt (by SIFTS) (Q9SRR8) | Arabidopsis thaliana (Mouse-ear cress) | |
| 9 | I (X) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8-B | polymer | 106 | 11986.0 | 1 | UniProt (Q8LGE7) Pfam (PF06747) | Arabidopsis thaliana (Mouse-ear cress) | |
| 10 | J (Z) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-A | polymer | 143 | 16145.6 | 1 | UniProt (Q8RWA7) Pfam (PF06212) | Arabidopsis thaliana (Mouse-ear cress) | Protein MATERNAL EFFECT EMBRYO ARREST 4 |
| 11 | K (a) | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | polymer | 65 | 7349.6 | 1 | UniProt (Q9C9Z5) Pfam (PF15879) | Arabidopsis thaliana (Mouse-ear cress) | |
| 12 | L (b) | At2g46540/F11C10.23 | polymer | 65 | 6810.2 | 1 | UniProt (Q9ZPY5) | Arabidopsis thaliana (Mouse-ear cress) | Expressed protein,F11C10.23/F11C10.23,Fiber |
| 13 | M (d) | Excitatory amino acid transporter | polymer | 81 | 9220.7 | 1 | UniProt (Q94AL6) | Arabidopsis thaliana (Mouse-ear cress) | |
| 14 | N (e) | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-B | polymer | 83 | 9914.1 | 1 | UniProt (Q9LZI6) Pfam (PF10200) | Arabidopsis thaliana (Mouse-ear cress) | |
| 15 | O (f) | At4g16450 | polymer | 106 | 11355.0 | 1 | UniProt (Q84W12) Pfam (PF10785) | Arabidopsis thaliana (Mouse-ear cress) | NADH-ubiquinone oxidoreductase |
| 16 | P (i) | P1 | polymer | 98 | 11808.2 | 1 | UniProt (A0A178W1I8) Pfam (PF17250) UniProt (by SIFTS) (Q9FYF8) | Arabidopsis thaliana (Mouse-ear cress) | |
| 17 | Q (u) | unknown | polymer | 30 | 2571.2 | 1 | Arabidopsis thaliana (Mouse-ear cress) | ||
| 18 | R (v) | Uncharacterized protein At2g27730, mitochondrial | polymer | 113 | 11965.5 | 1 | UniProt (Q9ZUX4) | Arabidopsis thaliana (Mouse-ear cress) | |
| 19 | S (x) | Gamma carbonic anhydrase-like 2, mitochondrial | polymer | 256 | 27985.1 | 1 | UniProt (Q9SMN1) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CAL2 |
| 20 | T (y) | Gamma carbonic anhydrase 2, mitochondrial | polymer | 278 | 30102.2 | 1 | UniProt (Q9C6B3) Pfam (PF00132) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CA2,Transcription factor APFI |
| 21 | U (z) | Gamma carbonic anhydrase 1, mitochondrial | polymer | 275 | 30010.0 | 1 | UniProt (Q9FWR5) | Arabidopsis thaliana (Mouse-ear cress) | GAMMA CA1 |
| 22 | V (H) | Ubiquinone-9 | non-polymer | 795.2 | 1 | Chemie (UQ9) PubChem (99490) PubChem (5280473) PubChem (97038296) PubChem (97038294) PubChem (97038295) PubChem (125181414) PubChem (137350099) | |||
| 23 | W, Y (H, N) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 2 | Chemie (PTY) PubChem (446872) PubChem (3330137) | |||
| 24 | X (M) | Lauryl Maltose Neopentyl Glycol | non-polymer | 1005.2 | 1 | Chemie (LMN) PubChem (49839603) PubChem (70678409) PubChem (75300949) PubChem (132285124) PubChem (153502978) PubChem (126731017) PubChem (172914192) | |||
| 25 | Z (O) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) PubChem (29936) | |||
| 26 | AA (v) | (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE | non-polymer | 763.1 | 1 | Chemie (PC7) PubChem (14389436) PubChem (449006) PubChem (5313171) | |||
| 27 | BA (y) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 28 | CA (y) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 1 | Chemie (PGT) PubChem (25267633) PubChem (449008) PubChem (102447212) PubChem (16040248) PubChem (172432040) | |||
| 29 | DA (z) | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE | non-polymer | 455.4 | 1 | Chemie (PSF) PubChem (17754227) PubChem (44354119) PubChem (101771308) PubChem (9547083) PubChem (9547088) PubChem (15409343) | |||
| 30 | EA (z) | Phosphatidylinositol | non-polymer | 887.1 | 1 | Chemie (T7X) PubChem (42607491) PubChem (21226108) PubChem (59423079) PubChem (71581204) PubChem (174696) PubChem (72280035) PubChem (101025742) PubChem (101668931) PubChem (102207642) PubChem (6441989) PubChem (10260108) PubChem (134744895) PubChem (123819699) PubChem (154815683) PubChem (162368813) PubChem (137350037) PubChem (162371041) PubChem (172878298) |
Sequence modifications
L: 1 - 669 (UniProt: B5TM94)
M: 1 - 495 (UniProt: B5TM93)
| PDB | External Database | Details |
|---|---|---|
| Phe 91 | Ser 91 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 326 | Pro 326 | conflict |
| Phe 378 | Ser 378 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 21 |
| Total formula weight | 475707.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 6246.4 | |
| All* | Total formula weight | 481954.1 |
