7AQO

yeast THO-Sub2 complex dimer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (G, A)	THO complex subunit 2	polymer	1601	184450.0	2	UniProt (A0A6A5Q535) Pfam (PF16134) Pfam (PF11732) Pfam (PF11262) UniProt (by SIFTS) (P53552)	Saccharomyces cerevisiae S288C
2	B, F (H, B)	THO complex subunit HPR1	polymer	720	84544.0	2	UniProt (P17629) Pfam (PF11957)	Saccharomyces cerevisiae S288C	Hyperrecombination protein 1
3	C, G (K, E)	TEX1 isoform 1	polymer	380	42315.2	2	UniProt (A0A6A5Q4V2) Pfam (PF00400) UniProt (by SIFTS) (P53851)	Saccharomyces cerevisiae S288C	Y55_G0044670.mRNA.1.CDS.1
4	D, H (L, F)	EM14S01-3B_G0007820.mRNA.1.CDS.1	polymer	400	45521.0	2	UniProt (A0A6A5Q316) Pfam (PF00271) Pfam (PF00270) UniProt (by SIFTS) (Q07478)	Saccharomyces cerevisiae S288C	HN1_G0007890.mRNA.1.CDS.1,JXXY16.1_G0007900.mRNA.1.CDS.1,SUB2 isoform 1,SX2_G0007910.mRNA.1.CDS.1,XXYS1_G0007860.mRNA.1.CDS.1
5	I, K (J, C)	BJ4_G0025130.mRNA.1.CDS.1	polymer	261	30340.3	2	UniProt (A0A6A5PZX4) Pfam (PF09432) UniProt (by SIFTS) (O13539)	Saccharomyces cerevisiae S288C	HLJ1_G0025020.mRNA.1.CDS.1,THP2 isoform 1,Y55_G0025210.mRNA.1.CDS.1
6	J, L (I, D)	THO complex subunit MFT1	polymer	392	45055.0	2	UniProt (P33441) Pfam (PF05615)	Saccharomyces cerevisiae S288C	Mitochondrial fusion target protein 1

Sequence modifications

G, A: 1 - 1597 (UniProt: A0A6A5Q535)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

L, F: 51 - 446 (UniProt: A0A6A5Q316)

PDB	External Database	Details
Gly 47	-	expression tag
Ala 48	-	expression tag
Ala 49	-	expression tag
Ser 50	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	864451.0
All*	Total formula weight	864451.0

*Water molecules are not included.