7AOV

Crystal Structure of a TRPM2 Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transient receptor potential cation channel subfamily M member 2	polymer	424	47997.5	2	UniProt (A0A0R4IMY7) Pfam (PF18139)	Danio rerio (Zebrafish Brachydanio rerio)
2	C, D (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	E, F (A, B)	water	water		18.0	412	Chemie (HOH)

Sequence modifications

A, B: 37 - 419 (UniProt: A0A0R4IMY7)

PDB	External Database	Details
Gly -4	-	expression tag
His -3	-	expression tag
Mse -2	-	expression tag
Leu -1	-	expression tag
Glu 0	-	expression tag
Mse 1	-	expression tag
Leu 2	-	expression tag
Gly 3	-	expression tag
Thr 4	-	expression tag
Ser 5	-	expression tag
Gly 6	-	expression tag
Val 7	-	expression tag
Lys 8	-	expression tag
Ile 9	-	expression tag
His 10	-	expression tag
Pro 11	-	expression tag
Asn 12	-	expression tag
Gly 13	-	expression tag
Asn 14	-	expression tag
Ser 15	-	expression tag
Asn 16	-	expression tag
Gln 17	-	expression tag
Leu 18	-	expression tag
Gly 19	-	expression tag
Val 20	-	expression tag
Gln 21	-	expression tag
Leu 22	-	expression tag
Glu 23	-	expression tag
Asn 24	-	expression tag
Val 25	-	expression tag
Lys 26	-	expression tag
Leu 27	-	expression tag
Thr 28	-	expression tag
Ser 29	-	expression tag
Leu 30	-	expression tag
Phe 31	-	expression tag
Lys 32	-	expression tag
Lys 33	-	expression tag
Leu 34	-	expression tag
Asp 35	-	expression tag
Lys 36	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95995.1
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	96125.9

*Water molecules are not included.