7AOP
Structure of NUDT15 in complex with inhibitor TH8321
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nucleotide triphosphate diphosphatase NUDT15 | polymer | 164 | 18635.0 | 1 | UniProt (Q9NV35) Pfam (PF00293) | Homo sapiens (human) | MutT homolog 2,MTH2,Nucleoside diphosphate-linked moiety X motif 15,Nudix motif 15,Nucleoside diphosphate-linked to another moiety X hydrolase 15,Nudix hydrolase 15 |
| 2 | B (A) | 2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione | non-polymer | 355.5 | 1 | Chemie (RTW) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 57 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18635.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 379.8 | |
| All* | Total formula weight | 19014.8 |
