7AOP

Structure of NUDT15 in complex with inhibitor TH8321

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000278	biological_process	mitotic cell cycle
A	0000302	biological_process	response to reactive oxygen species
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006195	biological_process	purine nucleotide catabolic process
A	0006203	biological_process	dGTP catabolic process
A	0008413	molecular_function	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
A	0009217	biological_process	purine deoxyribonucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0035539	molecular_function	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
A	0042178	biological_process	xenobiotic catabolic process
A	0042262	biological_process	DNA protection
A	0044715	molecular_function	8-oxo-dGDP phosphatase activity
A	0046872	molecular_function	metal ion binding
A	0047429	molecular_function	nucleoside triphosphate diphosphatase activity
A	0055086	biological_process	nucleobase-containing small molecule metabolic process
A	0061136	biological_process	regulation of proteasomal protein catabolic process
A	1901292	biological_process	nucleoside phosphate catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLU63
A	GLU67

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