7ANK

Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with half dimer of alpha-actinin-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Alpha-actinin-2	polymer	535	62561.1	1	UniProt (P35609) Pfam (PF00307) Pfam (PF00435)	Homo sapiens (Human)	Alpha-actinin skeletal muscle isoform 2,F-actin cross-linking protein
2	B (B)	Alpha-actinin-2	polymer	389	44609.0	1	UniProt (P35609) Pfam (PF00435) Pfam (PF08726)	Homo sapiens (Human)	Alpha-actinin skeletal muscle isoform 2,F-actin cross-linking protein
3	C (C)	Myozenin-1	polymer	209	21524.7	1	UniProt (Q9NP98) Pfam (PF05556)	Homo sapiens (Human)	Calsarcin-2,Filamin-,actinin- and telethonin-binding protein,Protein FATZ

Sequence modifications

A: 1 - 507 (UniProt: P35609)

PDB	External Database	Details
Ser 508	-	expression tag
Glu 509	-	expression tag
Arg 510	-	expression tag
Val 511	-	expression tag
Arg 512	-	expression tag
Asn 513	-	expression tag
Phe 514	-	expression tag
Glu 515	-	expression tag
Asp 516	-	expression tag
Pro 517	-	expression tag
Ala 518	-	expression tag
Ala 519	-	expression tag
Asn 520	-	expression tag
Lys 521	-	expression tag
Ala 522	-	expression tag
Arg 523	-	expression tag
Lys 524	-	expression tag
Glu 525	-	expression tag
Ala 526	-	expression tag
Glu 527	-	expression tag
Leu 528	-	expression tag
Ala 529	-	expression tag
Ala 530	-	expression tag
Ala 531	-	expression tag
Thr 532	-	expression tag
Ala 533	-	expression tag
Glu 534	-	expression tag
Gln 535	-	expression tag

B: 509 - 894 (UniProt: P35609)

PDB	External Database	Details
Gly 506	-	expression tag
Ser 507	-	expression tag
Ser 508	-	expression tag

C: 92 - 299 (UniProt: Q9NP98)

PDB	External Database	Details
Gly 91	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	128694.7
All*	Total formula weight	128694.7

*Water molecules are not included.