7AMK
Zebrafish RET Cadherin Like Domains 1 to 4.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase receptor Ret | polymer | 480 | 54610.3 | 2 | UniProt (A8E7C6) Pfam (PF17756) Pfam (PF00028) Pfam (PF17812) Pfam (PF17813) | Danio rerio (Zebrafish) | |
| 2 | C (C) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1219.1 | 1 | In PDB GlyTouCan (G55013TE) | |||
| 3 | D, E, I (D, E, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, G (F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G00395TQ) | |||
| 6 | J (J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 7 | K (K) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 8 | BA, CA, DA, L, M... (B, A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 9 | EA, O, P (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 10 | FA, GA, Q, R (B, A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 11 | JA, KA, S, U, Y (B, A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
| 12 | AA, HA, IA, LA, MA... (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 10 | Chemie (PEG) | |||
| 13 | NA (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 14 | OA, PA (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 502 (UniProt: A8E7C6)
| PDB | External Database | Details |
|---|---|---|
| Gln 259 | Asn 259 | engineered mutation |
| Gln 308 | Asn 308 | engineered mutation |
| Gln 390 | Asn 390 | engineered mutation |
| Gln 433 | Asn 433 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 109220.5 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 6155.7 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 3279.8 | |
| All* | Total formula weight | 118656.0 |
