7AMA
IL-17A in complex with small molecule modulators
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-17A | polymer | 109 | 12657.3 | 2 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (Human) | IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | C (B) | ~{N}-[(2~{S})-1,1-dicyclopropyl-3-[[4-(3,5-dimethyl-1~{H}-pyrazol-4-yl)phenyl]amino]-3-oxidanylidene-propan-2-yl]-2-propan-2-yl-pyrazole-3-carboxamide | non-polymer | 474.6 | 1 | Chemie (RMK) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25314.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 474.6 | |
| All* | Total formula weight | 25789.3 |
