7ALX

Sav-SOD: Chimeric Streptavidin-cSOD as Host for Artificial Metalloenzymes

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AAA, BBB)	Streptavidin,Superoxide dismutase [Cu-Zn],Streptavidin	polymer	194	20069.7	2	UniProt (P22629) UniProt (P0A609)	Streptomyces avidinii
2	C, D (AAA, BBB)	chlorido[(2S,4S)-4-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}methyl)-1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-yl]gold	non-polymer		794.2	2	Chemie (UFW) PubChem (156022778)
3	E, F (AAA, BBB)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

AAA, BBB: 14 - 47 (UniProt: P22629)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 1	-	expression tag
Ser 2	-	expression tag
Met 3	-	expression tag
Thr 4	-	expression tag
Gly 5	-	expression tag
Gly 6	-	expression tag
Gln 7	-	expression tag
Gln 8	-	expression tag
Met 9	-	expression tag
Gly 10	-	expression tag
Arg 11	-	expression tag
Asp 12	-	expression tag
Gln 13	-	expression tag

AAA, BBB: 48 - 82 (UniProt: P0A609)
AAA, BBB: 83 - 193 (UniProt: P22629)

PDB	External Database	Details
Ala 155	Lys 145	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40139.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1588.4
All*	Total formula weight	41727.8

*Water molecules are not included.