7ALQ

human GCH-GFRP inhibitory complex 7-deaza-GTP bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	GTP cyclohydrolase 1	polymer	209	23474.0	20	UniProt (P30793) Pfam (PF01227) In PDB	Homo sapiens (Human)	GTP cyclohydrolase I,GTP-CH-I
2	a, b, c, d, e...	GTP cyclohydrolase 1 feedback regulatory protein	polymer	87	9992.5	20	UniProt (P30047) Pfam (PF06399) In PDB	Homo sapiens (Human)	GFRP,GTP cyclohydrolase I feedback regulatory protein,p35
3	E, N, F, O, G...	ZINC ION	non-polymer		65.4	20	Chemie (ZN)
4	M, E, N, F, O...	7-deaza-GTP	non-polymer		522.2	20	Chemie (QBQ)
5	M, E, F, O, G...	7,8-DIHYDROBIOPTERIN	non-polymer		239.2	20	Chemie (HBI)
6	e, f, g, h, i...	POTASSIUM ION	non-polymer		39.1	20	Chemie (K)
7		water	water		18.0	2115	Chemie (HOH)

Sequence modifications

a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t: 1 - 84 (UniProt: P30047)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	40
	Total formula weight	669329.3
Non-Polymers*	Number of molecules	80
	Total formula weight	17318.6
All*	Total formula weight	686647.9

*Water molecules are not included.