7ALE

Crystal structure of human PAICS in complex with inhibitor 69

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Multifunctional protein ADE2	polymer	425	47135.1	2	UniProt (P22234) Pfam (PF01259) Pfam (PF00731) In PDB	Homo sapiens (Human)
2	A, B	2-azanyl-~{N}-[2-bromanyl-5-[4-[3-(dimethylamino)propylsulfonyl]piperazin-1-yl]phenyl]-1,3-oxazole-4-carboxamide	non-polymer		515.4	2	Chemie (RLK)
3	A, B	(2~{S})-2-[[5-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]imidazol-4-yl]car bonylamino]butanedioic acid	non-polymer		454.3	2	Chemie (OK8)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	94270.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1939.4
All*	Total formula weight	96209.6

*Water molecules are not included.