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7ALA

human GCH-GFRP inhibitory complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
GTP cyclohydrolase 1polymer20923474.05UniProt (P30793)
Pfam (PF01227)
Homo sapiens (Human)GTP cyclohydrolase I,GTP-CH-I
2F, G, H, I, J
(F, G, H, I, J)
GTP cyclohydrolase 1 feedback regulatory proteinpolymer879992.55UniProt (P30047)
Pfam (PF06399)
Homo sapiens (Human)GFRP,GTP cyclohydrolase I feedback regulatory protein,p35
3K, M, O, Q, S
(A, B, C, D, E)
ZINC IONnon-polymer65.45Chemie (ZN)
4L, N, P, R, T
(A, B, C, D, E)
2-azanyl-8-[(4-fluorophenyl)methylsulfanyl]-1,7-dihydropurin-6-onenon-polymer291.35Chemie (5RW)
5U, V, W, X, Y
(F, G, H, I, J)
SODIUM IONnon-polymer23.05Chemie (NA)
6AA, BA, CA, DA, EA...
(B, C, D, E, F...)
waterwater18.0769Chemie (HOH)
Sequence modifications
F, G, H, I, J: 1 - 84 (UniProt: P30047)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight167332.3
Non-Polymers*Number of molecules15
Total formula weight1898.5
All*Total formula weight169230.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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