7AKS
Human ADP-ribosylserine hydrolase ARH3 mutant E41A in complex with H2B-S7-mar peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (AAA, CCC, EEE, GGG) | ADP-ribose glycohydrolase ARH3 | polymer | 349 | 37796.3 | 4 | UniProt (Q9NX46) Pfam (PF03747) | Homo sapiens (human) | ADP-ribosylhydrolase 3,O-acetyl-ADP-ribose deacetylase ARH3,Poly(ADP-ribose) glycohydrolase ARH3,[Protein ADP-ribosylarginine] hydrolase-like protein 2,[Protein ADP-ribosylserine] hydrolase |
| 2 | B, D, F, H (BaB, DaD, FaF, HaH) | modified peptide | polymer | 11 | 1096.3 | 4 | Homo sapiens | ||
| 3 | DB, EB, I, J, MA... (GGG, AAA, EEE, CCC) | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
| 4 | AA, BA, CA, FB, GB... (CCC, GGG, AAA, EEE) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 19 | Chemie (EDO) | |||
| 5 | AB, BB, DA, EA, FA... (EEE, CCC, GGG, AAA) | ACETATE ION | non-polymer | 59.0 | 28 | Chemie (ACT) | |||
| 6 | CB, LA, PB, T (FaF, DaD, HaH, BaB) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 4 | Chemie (AR6) | |||
| 7 | QB, RB, SB, TB, UB... (AAA, BaB, CCC, DaD, EEE...) | water | water | 18.0 | 758 | Chemie (HOH) |
Sequence modifications
AAA, CCC, EEE, GGG: 19 - 363 (UniProt: Q9NX46)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Ala 41 | Glu 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 155570.2 | |
| Non-Polymers* | Number of molecules | 60 |
| Total formula weight | 5288.5 | |
| All* | Total formula weight | 160858.8 |
