7AK1
Human MALT1(329-729) in complex with a chromane urea containing inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | polymer | 404 | 45679.4 | 1 | UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703) | Homo sapiens (Human) | MALT lymphoma-associated translocation,Paracaspase |
| 2 | B (A) | 1-(3-chloranyl-4-methoxy-phenyl)-3-[7-[(3~{S})-3-(methoxymethyl)morpholin-4-yl]-2-methyl-pyrazolo[1,5-a]pyrimidin-6-yl]urea | non-polymer | 460.9 | 1 | Chemie (RJH) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A: 329 - 728 (UniProt: Q9UDY8)
| PDB | External Database | Details |
|---|---|---|
| Gly 325 | - | expression tag |
| Pro 326 | - | expression tag |
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45679.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 485.2 | |
| All* | Total formula weight | 46164.6 |
