7AIG
HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND L-GLUTAMATE TENOFOVIR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Gag-Pol polyprotein | polymer | 556 | 64022.4 | 2 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 BH10 | Pr160Gag-Pol |
2 | B, D | Gag-Pol polyprotein | polymer | 428 | 50039.5 | 2 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus type 1 BH10 | Pr160Gag-Pol |
3 | T, E | DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3') | polymer | 27 | 8383.4 | 2 | Human immunodeficiency virus type 1 BH10 | ||
4 | P, F | DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(DDG))-3') | polymer | 21 | 6474.3 | 2 | Homo sapiens | ||
5 | C | L-Glutamate Tenofovir | non-polymer | 416.3 | 1 | Chemie (RE5) | |||
6 | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 554 (UniProt: P03366)
B, D: 1 - 428 (UniProt: P03366)
PDB | External Database | Details |
---|---|---|
Met -1 | - | initiating methionine |
Val 0 | - | expression tag |
Cys 258 | Gln 857 | engineered mutation |
Ser 280 | Cys 879 | engineered mutation |
Asn 498 | Asp 1097 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 280 | Cys 879 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 257839.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 416.3 | |
All* | Total formula weight | 258255.4 |