7AHU
Anti-FX Fab of mim8 in complex with human FXa
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C (L, A) | Anti-FX Fab of mim8 light chain | polymer | 216 | 23721.3 | 2 | Homo sapiens (Human) | ||
2 | B, D (H, B) | Anti-FX Fab of mim8 heavy chain | polymer | 222 | 24033.9 | 2 | Homo sapiens (Human) | ||
3 | E, G (C, E) | Coagulation factor X | polymer | 241 | 27201.1 | 2 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (Human) | Stuart factor,Stuart-Prower factor |
4 | F, H (D, F) | Coagulation factor X | polymer | 58 | 6478.4 | 2 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (Human) | Stuart factor,Stuart-Prower factor |
5 | I, K (C, E) | L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide | non-polymer | 395.9 | 2 | Chemie (0GJ) | |||
6 | J, L (C, E) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
7 | M, N, O, P, Q... (L, H, A, B, C...) | water | water | 18.0 | 444 | Chemie (HOH) |
Sequence modifications
D, F: 252 - 308 (UniProt: P00742)
PDB | External Database | Details |
---|---|---|
Met 251 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 162869.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 871.9 | |
All* | Total formula weight | 163741.1 |