7AB8
Crystal structure of a GDNF-GFRalpha1 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | GDNF family receptor alpha | polymer | 209 | 23366.5 | 1 | UniProt (Q98TT9) Pfam (PF02351) In PDB | Danio rerio (Zebrafish) | |
2 | B | Glial cell line-derived neurotrophic factor | polymer | 98 | 11281.8 | 1 | UniProt (Q98TU0) Pfam (PF00019) In PDB | Danio rerio (Zebrafish) | zGDNF |
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
6 | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 150 - 352 (UniProt: Q98TT9)
PDB | External Database | Details |
---|---|---|
Gly 353 | - | expression tag |
Ser 354 | - | expression tag |
Glu 355 | - | expression tag |
Phe 356 | - | expression tag |
Leu 357 | - | expression tag |
Glu 358 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34648.4 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 840.9 | |
All* | Total formula weight | 35913.7 |