7AB8
Crystal structure of a GDNF-GFRalpha1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GDNF family receptor alpha | polymer | 209 | 23366.5 | 1 | UniProt (Q98TT9) Pfam (PF02351) | Danio rerio (Zebrafish) | |
| 2 | B (B) | Glial cell line-derived neurotrophic factor | polymer | 98 | 11281.8 | 1 | UniProt (Q98TU0) Pfam (PF00019) | Danio rerio (Zebrafish) | zGDNF |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | I, J, K, L, M (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 150 - 352 (UniProt: Q98TT9)
| PDB | External Database | Details |
|---|---|---|
| Gly 353 | - | expression tag |
| Ser 354 | - | expression tag |
| Glu 355 | - | expression tag |
| Phe 356 | - | expression tag |
| Leu 357 | - | expression tag |
| Glu 358 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34648.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 840.9 | |
| All* | Total formula weight | 35913.7 |
