7AB0

Apo crystal structure of the MerTK kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein kinase Mer	polymer	298	34381.8	1	UniProt (Q12866) Pfam (PF07714) In PDB	Homo sapiens (Human)	Proto-oncogene c-Mer,Receptor tyrosine kinase MerTK
2	A	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
3		water	water		18.0	132	Chemie (HOH)

Sequence modifications

A: 571 - 864 (UniProt: Q12866)

PDB	External Database	Details
Gly 567	-	expression tag
Ser 568	-	expression tag
His 569	-	expression tag
Met 570	-	expression tag
Arg 591	Lys 591	engineered mutation
Arg 693	Lys 693	engineered mutation
Arg 702	Lys 702	engineered mutation
Arg 856	Lys 856	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34381.8
Non-Polymers*	Number of molecules	5
	Total formula weight	177.3
All*	Total formula weight	34559.0

*Water molecules are not included.