7AAJ
Human porphobilinogen deaminase in complex with cofactor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Porphobilinogen deaminase | polymer | 363 | 39527.1 | 2 | UniProt (P08397) Pfam (PF01379) Pfam (PF03900) | Homo sapiens (Human) | PBG-D,Hydroxymethylbilane synthase,HMBS,Pre-uroporphyrinogen synthase |
| 2 | C, E (B, A) | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid | non-polymer | 420.4 | 2 | Chemie (DPM) | |||
| 3 | D, F, G (B, A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I (B, A) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 361 (UniProt: P08397)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79054.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1117.1 | |
| All* | Total formula weight | 80171.4 |
