7AAJ

Human porphobilinogen deaminase in complex with cofactor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004418	molecular_function	hydroxymethylbilane synthase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006779	biological_process	porphyrin-containing compound biosynthetic process
A	0006782	biological_process	protoporphyrinogen IX biosynthetic process
A	0006783	biological_process	heme biosynthetic process
A	0006784	biological_process	heme A biosynthetic process
A	0006785	biological_process	heme B biosynthetic process
A	0016740	molecular_function	transferase activity
A	0018160	biological_process	peptidyl-pyrromethane cofactor linkage
A	0033014	biological_process	tetrapyrrole biosynthetic process
B	0004418	molecular_function	hydroxymethylbilane synthase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006779	biological_process	porphyrin-containing compound biosynthetic process
B	0006782	biological_process	protoporphyrinogen IX biosynthetic process
B	0006783	biological_process	heme biosynthetic process
B	0006784	biological_process	heme A biosynthetic process
B	0006785	biological_process	heme B biosynthetic process
B	0016740	molecular_function	transferase activity
B	0018160	biological_process	peptidyl-pyrromethane cofactor linkage
B	0033014	biological_process	tetrapyrrole biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00533
Number of Residues	17
Details	PORPHOBILINOGEN_DEAM Porphobilinogen deaminase cofactor-binding site. ERaFlrhLeGGCsVPVA

Chain	Residue	Details
B	GLU250-ALA266

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"S-(dipyrrolylmethanemethyl)cysteine","evidences":[{"source":"PubMed","id":"18936296","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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