7A8P
Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA-directed RNA polymerase, mitochondrial | polymer | 1143 | 129803.1 | 1 | UniProt (O00411) Pfam (PF14700) Pfam (PF00940) In PDB | Homo sapiens (Human) | MtRPOL |
2 | A | (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid | non-polymer | 473.9 | 1 | Chemie (R4Q) |
Sequence modifications
A: 105 - 1230 (UniProt: O00411)
PDB | External Database | Details |
---|---|---|
Met 88 | - | initiating methionine |
Gly 89 | - | expression tag |
His 90 | - | expression tag |
His 91 | - | expression tag |
His 92 | - | expression tag |
His 93 | - | expression tag |
His 94 | - | expression tag |
His 95 | - | expression tag |
Glu 96 | - | expression tag |
Asn 97 | - | expression tag |
Leu 98 | - | expression tag |
Tyr 99 | - | expression tag |
Phe 100 | - | expression tag |
Gln 101 | - | expression tag |
Ser 102 | - | expression tag |
Asn 103 | - | expression tag |
Ala 104 | - | expression tag |
Ala 555 | Glu 555 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 129803.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 473.9 | |
All* | Total formula weight | 130277.0 |