7A77
Crystal structure of RXR alpha LBD in complexes with palmitic acid and GRIP-1 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 242 | 27074.3 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 14 | 1743.0 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | D (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 223 - 462 (UniProt: P19793)
B: 471 - 484 (UniProt: Q15596)
| PDB | External Database | Details |
|---|---|---|
| Ser 221 | - | expression tag |
| Met 222 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 484 | Ser 699 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28817.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 540.1 | |
| All* | Total formula weight | 29357.5 |
